Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Structure and function of parallel pathways in the primate early visual system.

Edward M Callaway1

  • 1Systems Neurobiology Laboratories, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA. callaway@salk.edu

The Journal of Physiology
|May 21, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A disinhibitory basal forebrain-to-cortex projection supports sustained attention.

Cell·2026
Same author

Protocol for mapping neural circuit connectivity with START: Single transcriptome assisted rabies tracing.

STAR protocols·2026
Same author

Asymmetric cortical projections to striatal direct and indirect pathways distinctly control actions.

eLife·2025
Same author

Complementary Organization of Mouse Driver and Modulator Cortico-thalamo-cortical Circuits.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2025
Same author

Transcriptomic cell-type specificity of local cortical circuits.

Neuron·2024
Same author

Parallel Streams of Direct Corticogeniculate Feedback from Mid-level Extrastriate Cortex in the Macaque Monkey.

eNeuro·2024
Same journal

Diving exposure and pulmonary stress.

The Journal of physiology·2026
Same journal

Systems modelling of mitochondrial dynamics in different exercise regimes.

The Journal of physiology·2026
Same journal

Central leptin resistance precedes obesity and drives early endocrine dysfunction.

The Journal of physiology·2026
Same journal

Decoding the molecular memory of obesity using machine learning and microRNA dynamics.

The Journal of physiology·2026
Same journal

Kinematic-calcium loops unravel impaired excitation-contraction coupling in MELAS-affected cardioids.

The Journal of physiology·2026
Same journal

hERG1 channels and potential therapeutics for long QT syndrome.

The Journal of physiology·2026
See all related articles

Investigating primate visual processing reveals distinct retinal ganglion cell (RGC) pathways. The magnocellular (M) and parvocellular (P) pathways are well-defined, but others remain unclear.

Area of Science:

  • Neuroscience
  • Visual System Research
  • Primate Visual Processing

Background:

  • The primate visual system utilizes parallel processing streams originating from diverse retinal ganglion cell (RGC) types.
  • Understanding the connectivity of these RGC types to central visual structures like the lateral geniculate nucleus (LGN) and visual cortex is crucial but challenging.
  • Existing evidence linking specific RGC types to downstream cells is often indirect.

Purpose of the Study:

  • To review and evaluate the anatomical and functional evidence connecting RGC types to central visual pathways.
  • To assess the strength of inferences regarding RGC-to-LGN and RGC-to-cortex connections.
  • To clarify the origins and definitions of visual pathways, including the koniocellular (K) pathway.

Main Methods:

Related Experiment Videos

  • Review of existing anatomical and functional studies on primate visual pathways.
  • Evaluation of indirect evidence linking specific retinal ganglion cell (RGC) types to neuronal populations in the lateral geniculate nucleus (LGN) and visual cortex.
  • Assessment of the segregation and convergence of visual information streams.

Main Results:

  • Strong evidence supports parasol RGCs forming the magnocellular (M) pathway and midget RGCs forming the parvocellular (P) pathway.
  • The M and P pathways maintain segregation through the LGN to the primary visual cortex.
  • The origins and connections of other RGC types, potentially forming the koniocellular (K) pathway, remain less certain.

Conclusions:

  • The magnocellular (M) and parvocellular (P) pathways are well-established routes for visual information processing in primates.
  • Significant ambiguity persists regarding the precise connections of numerous other RGC types to the LGN.
  • Further research is needed to definitively characterize additional visual pathways, such as the koniocellular (K) pathway, and their constituent RGCs.