Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Peripheral vascular endothelial function in essential hyperhidrosis.

Ali Metin Esen1, Irfan Barutcu, Semsettin Karaca

  • 1Kosuyolu Heart Education and Research Hospital, Department of Cardiology, Istanbul, Turkey.

Circulation Journal : Official Journal of the Japanese Circulation Society
|May 26, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Early Echocardiographic Changes Following Transcatheter Aortic Valve Implantation: A Comparative Analysis of Different Transcatheter Aortic Valve Systems.

Journal of cardiovascular development and disease·2026
Same author

Response to the Letter Regarding "Relationship Between the Severity of Coronary Artery Disease and Renal Function".

Angiology·2026
Same author

Electrocardiographic atrial cardiomyopathy markers in sinus rhythm and the risk of incident atrial fibrillation and ischemic stroke a retrospective cohort study.

Journal of electrocardiology·2026
Same author

Relationship Between the Severity of Coronary Artery Disease and Renal Function.

Angiology·2026
Same author

Early-Phase Exercise-Based Comprehensive Cardiac Rehabilitation Program after Myocardial Infarction: A Randomized Controlled Trial.

Acta Cardiologica Sinica·2026
Same author

TAVI Performance at a Single Center over Several Years: Procedural and Clinical Outcomes.

Medicina (Kaunas, Lithuania)·2026
Same journal

Non-Culprit Lesion Plaque Vulnerability Progression and Regression Assessed by Serial Optical Coherence Tomography Imaging.

Circulation journal : official journal of the Japanese Circulation Society·2026
Same journal

Reduction in Heart Failure Hospitalizations Through Real-World HeartLogic<sup>TM</sup> Alert Response　- A Multicenter Study in Japan.

Circulation journal : official journal of the Japanese Circulation Society·2026
Same journal

JCS/JPCPHS 2025 Guideline on Pulmonary Hypertension and Pulmonary Embolism/Deep Vein Thrombosis.

Circulation journal : official journal of the Japanese Circulation Society·2026
Same journal

Cardiac Stereotactic Body Radiotherapy for Refractory Ventricular Tachycardia　- Target Definition, Dose Distribution, and Clinical Trajectory.

Circulation journal : official journal of the Japanese Circulation Society·2026
Same journal

Myocardial Perfusion and Fluorodeoxyglucose Uptake Patterns in Cardiac Sarcoidosis Stratified by Diagnostic Category and Systemic Involvement.

Circulation journal : official journal of the Japanese Circulation Society·2026
Same journal

A High Level of Calculated Small Dense Low-Density Lipoprotein Cholesterol Is an Independent Risk Factor for the Progression of Renal Impairment.

Circulation journal : official journal of the Japanese Circulation Society·2026
See all related articles

Essential hyperhidrosis, a disorder of the eccrine sweat glands, does not impair endothelium-dependent vasodilation in large arteries. This suggests localized eccrine gland dysfunction rather than a generalized vascular endothelium disorder.

Area of Science:

  • Cardiovascular Physiology
  • Sweat Gland Biology
  • Endothelial Function

Background:

  • Essential hyperhidrosis is linked to sympathetic overactivity.
  • The role of vascular endothelium in this condition is unclear.

Purpose of the Study:

  • To investigate endothelium-dependent vasodilator function in patients with essential hyperhidrosis.

Main Methods:

  • High-resolution ultrasound was used to measure brachial artery diameter.
  • Flow-mediated dilatation (FMD) and nitroglycerin-induced dilatation (NTG) were assessed.
  • 18 patients with essential hyperhidrosis and 24 healthy controls were studied.

Main Results:

  • Baseline brachial artery diameter and FMD were comparable between groups (p=0.8 and p=0.1, respectively).

Related Experiment Videos

  • Peak reactive hyperemia flow velocity was similar in both groups (p=0.5).
  • Nitroglycerin-induced dilatation did not differ significantly between patients and controls (p=0.3).

    • Conclusions:

    • Endothelium-dependent vasodilation in large conduit arteries is preserved in essential hyperhidrosis.
    • Essential hyperhidrosis appears to be a localized disorder of eccrine sweat glands, not a generalized vascular endothelium issue.