Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

En-bloc esophagectomy--the three-field dissection.

Nasser Altorki1

  • 1Weill Medical College of Cornell University, 525 East 68th Street, New York, NY 10021, USA. nkaltork@med.cornell.edu

The Surgical Clinics of North America
|June 2, 2005
PubMed
Summary

Radical esophagectomy with extensive lymph node dissection offers a potential improvement for esophageal cancer treatment. This approach is examined for its technique and outcomes, addressing current therapeutic controversies.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Patient-derived organoids across cancers reveal conserved tumor heterogeneity and actionable therapeutic vulnerabilities.

Science advances·2026
Same author

STS Expert Consensus Document (2026) on Addressing Definition and Practices of Sublobar Resection in Non-small Cell Lung Cancer.

The Annals of thoracic surgery·2026
Same author

Machine Learning Assessment of Pathologic Response in Lung Cancer Resections After Neoadjuvant Therapy-IASLC MPR Project.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer·2026
Same author

Tumor immune microenvironment reconstitution in patient-derived organoids enables therapy modeling for NSCLC.

Cell reports methods·2026
Same author

Sublobar resection is the preferred surgical strategy for clinical stage IA lung cancers presenting as subsolid nodule.

JTCVS open·2026
Same author

Propionate metabolism is dysregulated in non-small cell lung cancer patients and EGFR-mutant drug-tolerant persister cells.

Scientific reports·2026

Area of Science:

  • Oncology
  • Surgical Oncology
  • Gastroenterology

Background:

  • Esophageal cancer treatment remains controversial, with standard surgical resection yielding high local recurrence (30-60%) and poor 5-year survival (20-25%).
  • Induction therapy has not significantly improved survival rates in current esophageal cancer treatment protocols.

Purpose of the Study:

  • To examine the rationale, technique, and results of radical esophagectomy.
  • To evaluate the role of extended lymph node dissection (two-field and three-field) in esophageal cancer management.

Main Methods:

  • Review of radical esophagectomy procedures.
  • Analysis of lymph node dissection techniques (two-field and three-field).
  • Examination of outcomes data for radical esophagectomy.

Related Experiment Videos

Main Results:

  • Standard esophagectomy results in high recurrence and low survival rates.
  • Radical esophagectomy and extensive lymphadenectomy are explored as potentially superior treatment modalities.
  • The article details the technical aspects and observed outcomes of these advanced surgical methods.

Conclusions:

  • Radical esophagectomy, incorporating two-field and three-field lymph node dissection, is presented as a critical area of investigation for improving esophageal cancer outcomes.
  • Further research into radical surgical techniques is warranted to address the limitations of current esophageal cancer treatments.