Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Preconditioning: gender effects.

Jeffrey M Pitcher1, Meijing Wang, Ben M Tsai

  • 1Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA.

The Journal of Surgical Research
|June 7, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A New Taxonomic Placement of <i>Cochylis discerta</i> (Lepidoptera: Tortricidae) to <i>Falseuncaria</i> Supported by Congruent Mitogenomic and Morphological Evidence.

Ecology and evolution·2026
Same author

Measurement of <sup>227</sup>Ac by Isotopic Ratio with <sup>225</sup>Ac Using ICP-MS.

ACS omega·2025
Same author

Pulmonary Autograft Mitral Valve Replacement (Ross II Procedure): More Than Two Decades of Follow-up From a Single Center in the United States.

World journal for pediatric & congenital heart surgery·2025
Same author

Annotated list of the Tortricidae (Lepidoptera) of Honduras.

Zootaxa·2025
Same author

Checklist of the Tribe Eucosmini Obraztsov, 1946 (Lepidoptera: Tortricidae: Olethreutinae) from Taiwan.

Insects·2025
Same author

Outcomes and Predictors of Failure of Systemic-to-Pulmonary Shunts: Experience of a Single Institution Over 14 Years.

World journal for pediatric & congenital heart surgery·2025
Same journal

Emergency Surgical Cricothyrotomy Videos Online: Reliability and Training Quality Evaluation.

The Journal of surgical research·2026
Same journal

Management of Concomitant Traumatic Abdominal Vascular and Gastrointestinal Injuries: A Descriptive Study.

The Journal of surgical research·2026
Same journal

Article Processing Charges in General Surgery Journals: Implications for Equitable Publishing Access in Low-Income and Middle-Income Countries.

The Journal of surgical research·2026
Same journal

Association of Distal Internal Carotid Artery Tortuosity With Carotid Artery Stenting Outcomes.

The Journal of surgical research·2026
Same journal

Appendectomy and Subsequent Type 2 Diabetes - A National Cohort study.

The Journal of surgical research·2026
Same journal

Perceptions and Barriers to Intraoperative Non-technical Skills Feedback in General Surgery: A Mixed-Methods Study.

The Journal of surgical research·2026
See all related articles

Preconditioning protects against injury by upregulating cellular defenses. This review explores sex differences in preconditioning mechanisms, noting females may have a protective advantage against acute insults.

Area of Science:

  • Physiology
  • Cellular Biology
  • Neuroscience

Background:

  • Preconditioning confers protection against subsequent injury through upregulated cellular responses.
  • Females often exhibit a protective advantage against acute insults compared to males.
  • Sex differences in preconditioning mechanisms remain under-explored, impacting clinical outcome variability.

Purpose of the Study:

  • To review sex differences in response to acute injury.
  • To discuss the fundamental mechanisms of preconditioning.
  • To examine sex-based variations in preconditioning mechanisms.

Main Methods:

  • Literature review of studies on preconditioning and sex differences in injury response.
  • Analysis of cellular and molecular mechanisms underlying preconditioning.

Related Experiment Videos

  • Comparison of male and female responses to acute insults and preconditioning stimuli.

    • Main Results:

    • Preconditioning involves acute and delayed cellular defense mechanisms.
    • Females demonstrate a protective advantage in response to acute injury.
    • Significant gaps exist in understanding sex-specific preconditioning pathways.

    Conclusions:

    • Understanding sex differences in preconditioning is crucial for personalized medicine.
    • Further research is needed to elucidate the molecular basis of sex differences in preconditioning.
    • Pre-morbid preconditioning status may influence patient outcomes differently between sexes.