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Case report: mixed-field agglutination in a patient with a weak D antigen presenting as a possible fetal-maternal
P J Unger1, J Rapini, F DelMores
1LifeSource, 530 E. 31st Street, Chicago, IL 60616, USA.
A gravida 1, para O, 17-year-old black female was found on prenatal testing to be group O, Du+, the latter test showing many unagglutinated cells. Because of the mixed-field appearance, the patient was thought initially to have bad a fetal-maternal hemorrhage. Additional red cell typings were performed, but no other apparent mixed-field reactions were observed. The Kleihauer- Betke test and hemoglobin electrophoresis indicated that the mixed-field agglutination was not due to a fetal-maternal hemorrhage. Thus, the finding of a mixed-field D typing could he explained best by a weak D antigen.
A gravida 1, para O, 17-year-old black female was found on prenatal testing to be group O, Du+, the latter test showing many unagglutinated cells. Because of the mixed-field appearance, the patient was thought initially to have bad a fetal-maternal hemorrhage. Additional red cell typings were performed, but no other apparent mixed-field reactions were observed. The Kleihauer- Betke test and hemoglobin electrophoresis indicated that the mixed-field agglutination was not due to a fetal-maternal hemorrhage. Thus, the finding of a mixed-field D typing could he explained best by a weak D antigen.
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