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Updated: Aug 17, 2026

A Novel Method: Super-selective Adrenal Venous Sampling
Published on: September 15, 2017
A pheochromocytoma causing limited coagulopathy with hemoptysis
Yoko Kimura1, Hideki Ozawa, Mihoko Igarashi
1Institute of Oriental Medicine, Tokyo Women's Medical University School of Medicine, 2-4-1 Nishishin juku, Shin juku-ku, Tokyo 163-0804, Japan. ykimura@iom.twmu.ac.jp
Abstract:
We treated a 59-year-old woman presenting with hemoptysis, a rare symptom of pheochromocytoma. Multiple factors including hypertension caused by sudden catecholamine release may result in pulmonary edema. It should be noted that the increased activation of coagulation cascade, which was demonstrated by increased thrombin-antithrombin III complex (TAT) and prothrombin fragment factor 1 and 2 (F1 + 2), as well as endothelial or platelet stimulation evidenced by the increased plasma von Willebrand factor, may have contributed to hemoptysis. These abnormalities were normalized after adrenalectomy. Our case indicates the important role of catecholamine in coagulopathy and possibly in vasculopathy.
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