Related Experiment Video

Updated: Aug 16, 2026

Spinal Cord Neurons Isolation and Culture from Neonatal Mice
07:49

Spinal Cord Neurons Isolation and Culture from Neonatal Mice

Published on: July 11, 2017

Neuroprotective effect of cytoflavin during compression injury of the spinal cord

V V Bul'on1, N N Kuznetsova, E N Selina

  • 1Department of Neuropharmacology, Institute of Experimental Medicine, Russia. sns@iem.spb.ru

Bulletin of Experimental Biology and Medicine
|July 20, 2005
PubMed

More Related Videos

Calibrated Forceps Model of Spinal Cord Compression Injury09:41

Calibrated Forceps Model of Spinal Cord Compression Injury

Published on: April 24, 2015

Synergetic Use of Neural Precursor Cells and Self-assembling Peptides in Experimental Cervical Spinal Cord Injury11:57

Synergetic Use of Neural Precursor Cells and Self-assembling Peptides in Experimental Cervical Spinal Cord Injury

Published on: February 23, 2015

Related Concept Videos

Spinal Cord Injury ll: Pathophysiology01:14

Spinal Cord Injury ll: Pathophysiology

Spinal cord injury progresses through two interconnected phases: primary injury and secondary injury.Primary InjuryPrimary injury happens at the moment of trauma and involves immediate mechanical damage to the spinal cord.Compression happens when broken vertebrae, herniated discs, or accumulating blood (such as a hematoma) press directly against the spinal cord, distorting its normal shape and function. In cases of contusion, the cord is bruised by a blunt force (like penetrating injuries or...
Secondary Spinal Cord Injury llI: Pathophysiology01:25

Secondary Spinal Cord Injury llI: Pathophysiology

Early Ischemia and Ionic ImbalanceWithin minutes of spinal cord injury, a secondary cascade begins, progressing over hours to weeks. Vascular damage reduces blood flow, causing ischemia and mitochondrial dysfunction. ATP depletion leads to ion pump failure, membrane depolarization, sodium influx, potassium efflux, and water accumulation, resulting in cellular swelling. Increased intracellular calcium further disrupts mitochondria and accelerates cellular injury.Excitotoxicity and Neuronal...