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Simultaneous multislice imaging with slice-multiplexed RF pulses.

K J Lee1, J M Wild, P D Griffiths

  • 1Academic Unit of Radiology, University of Sheffield, UK. k.j.lee@sheffield.ac.uk

Magnetic Resonance in Medicine
|September 13, 2005
PubMed
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This study introduces a novel simultaneous multislice imaging technique using phase-encoded radiofrequency pulses. While avoiding distortions and extra hardware, it may increase scan time and cause slice crosstalk due to susceptibility gradients.

Area of Science:

  • Magnetic Resonance Imaging (MRI)
  • Medical Physics
  • Biomedical Engineering

Background:

  • Simultaneous multislice (SMS) imaging accelerates MRI acquisition by exciting and acquiring multiple slices concurrently.
  • Existing SMS methods face challenges including image distortion, increased acquisition time, and hardware requirements.

Purpose of the Study:

  • To present a novel SMS imaging method utilizing slice-specific phase profiles to enable simultaneous slice excitation and unaliasing.
  • To evaluate the performance of this new SMS technique in phantom and in vivo imaging scenarios.

Main Methods:

  • A multislice radiofrequency (RF) pulse with unique linear phase profiles for each slice was employed.
  • Extra slice-select gradient lobes were used during readout to unalias individual slices sequentially.

Related Experiment Videos

  • The method was tested using both gradient-echo and spin-echo sequences on phantoms and in vivo.

    • Main Results:

    • The proposed method successfully unaliased slices without the distortion typically caused by slice-select gradients in other SMS techniques.
    • No additional hardware or extra imaging views were required, simplifying implementation.
    • A trade-off was observed: the need for one echo per slice extended the readout period, potentially leading to slice crosstalk from susceptibility gradients and increasing the minimum repetition time (TR).

    Conclusions:

    • This phase-profile-based SMS method offers a viable alternative for accelerated MRI, mitigating common distortions.
    • The increased readout duration and potential for crosstalk are key limitations to consider for specific applications.
    • Further optimization may be needed to address susceptibility effects and minimize TR for broader clinical utility.