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Leptomeningeal cancer in the pediatric patient
Kathleen A Neville1, Susan M Blaney
1Texas Children's Cancer Center, Baylor College of Medicine Houston, TX 77030, USA.
Abstract:
The treatment and prophylaxis of leptomeningeal leukemia and lymphoma in children has dramatically improved disease control and long-term survival. However, the treatment of other leptomeningeal cancers has been less successful and the neurologic morbidity associated with central nervous system-directed therapy has a significant long-term impact on quality of life. Further research is critical to identify new therapeutic strategies for children with or at high risk for leptomeningeal cancer.
