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Updated: Aug 15, 2026
Seeding and Implantation of a Biosynthetic Tissue-engineered Tracheal Graft in a Mouse Model
Published on: April 1, 2019
[Experimental study of tracheal defect repair with shape-memory titanium-nickel alloy net]
Jiasheng Luo1, Wenxian Chen, Pengcheng Cui
1Department of Otolaryngology, Tangdu Hospital, Fourth Military Medical University, Xi'an, 710038, China. l-js@163.com
Objective:
To investigate the feasibility of trachea defect repair with "C" shape shape-memory titanium-nickel alloy net (CSSMAN).
Method:
The CSSMAN substitute for the tracheal cartilage and the skin tube for the tracheal mucosa in order to form a new "trachea" shape structure to repair the mongrel dogs trachea defect.
Result:
Four dogs were successfully decannulate, computerized tomography (CT) examination and fibrotracheoscopy examination showed the CSSMAN located perfectly and the airway is wide enough for breath. One dog failed to decannulate due to the infection.
Conclusion:
It is a promising choice to repair the trachea defect with CSSMAN by two-stage procedure.
