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Asthma pharmacogenomics.

Gregory A Hawkins1, Scott T Weiss, Eugene R Bleecker

  • 1Center for Human Genomics, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157, USA. ghawkins@wfubmc.edu

Immunology and Allergy Clinics of North America
|November 1, 2005
PubMed
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Future asthma treatments may use genetic tests for personalized medication, reducing side effects. However, widespread pharmacogenomics adoption depends on cost, usability, and result interpretation, not just test availability.

Area of Science:

  • Pharmacogenomics
  • Asthma Therapeutics
  • Genetic Testing

Background:

  • Personalized medicine is advancing asthma treatment.
  • Genetic information can guide medication selection.
  • Reducing adverse drug reactions is a key goal.

Purpose of the Study:

  • To explore the future application of pharmacogenomics in asthma therapy.
  • To identify factors influencing the adoption of pharmacogenomic testing for asthma.

Main Methods:

  • Review of current trends in pharmacogenomics and asthma treatment.
  • Analysis of potential barriers and facilitators for clinical implementation.

Main Results:

  • Genetic testing is expected to precede asthma medication prescription.

Related Experiment Videos

  • Not all genetic factors influencing drug response need to be known for initial pharmacogenomic application.
  • Test availability alone may not drive adoption.
  • Conclusions:

    • Pharmacogenomics holds promise for optimizing asthma pharmacotherapy.
    • Widespread use of pharmacogenomics in asthma care hinges on practical considerations like cost and interpretability.
    • Ease of use and affordability are critical for integrating genetic tests into routine asthma management.