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Updated: Aug 14, 2026

Echocardiographic Assessment Using Subxiphoid-Only Examination for Hypotensive Patients
Published on: April 18, 2025
Echocardiography in the evaluation of patients in chest pain units
1william.lewis@ucdmc.ucdavis.edu
Insights
Echocardiography detects cardiac wall motion abnormalities, an early sign of myocardial ischemia, potentially before ECG changes or angina. This makes it a sensitive tool for diagnosing ischemia, especially in emergency settings.
Area of Science:
- Cardiology
- Diagnostic Imaging
Background:
- Echocardiography detects cardiac wall motion abnormalities preceding ECG changes and angina during induced ischemia.
- Cardiac wall motion abnormalities are a sensitive indicator of myocardial ischemia.
- Echocardiography is reliable for assessing cardiac function and diagnosing myocardial ischemia.
Purpose of the Study:
- To evaluate the sensitivity of echocardiography for detecting myocardial ischemia.
- To assess the utility of echocardiography in emergency department patients with suspected myocardial ischemia.
- To compare echocardiography with left ventriculography in acute ST-elevation myocardial infarction.
Main Methods:
- Percutaneous angioplasty to induce ischemic cascade in a cardiac catheterization laboratory.
- Echocardiography to assess cardiac wall motion abnormalities.
- Comparison with electrocardiography, angina, and invasive left ventriculography.
Main Results:
- Echocardiographic wall motion abnormalities precede ECG abnormalities and angina.
- Echocardiography is comparable to left ventriculography in detecting wall motion abnormalities in acute ST-elevation MI.
- The utility of echocardiography in low-risk chest pain patients with nondiagnostic presentations is less established.
Conclusions:
- Echocardiography is a sensitive method for identifying myocardial ischemia.
- Echocardiography aids in diagnosis and risk assessment for myocardial ischemia in the ED.
- Further research is needed on echocardiography's role in low-risk chest pain populations.
Abstract:
Using percutaneous angioplasty to induce the ischemic cascade in the cardiac catheterization laboratory, echocardiographic wall motion abnormalities have been documented to precede electrocardiographic abnormalities and angina. Therefore, detection of cardiac wall motion abnormalities is potentially more sensitive than the history, physical examination, and ECG for identification of myocardial ischemia. Echocardiography is highly reliable for assessing cardiac wall motion and, thus, it has been used for diagnosis and risk assessment in patients presenting to the emergency department (ED) with symptoms suggestive of myocardial ischemia. In patients who have acute ST-elevation myocardial infarction (MI), echocardiography is comparable to invasive left ventriculography for detecting wall motion abnormalities. However, the usefulness of echocardiography in the low-risk population that has chest pain of uncertain origin and a nondiagnostic initial presentation is less well established.
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