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Published on: October 9, 2016
Ultrastructural study of chitosan effects on Klebsiella and staphylococci
L V Didenko1, D V Gerasimenko, N D Konstantinova
1Laboratory of Microorganism Anatomy, N. F. Gamaleya Institute of Epidemiology and Microbiology, Russian Academy of Medical Sciences, Moscow.
Abstract:
Antibacterial effect of chitosan on the morphofunctional organization of clinical strains of Klebsiella pneumoniae and Staphylococcus aureus was studied by transmission electron microscopy. Chitosan promoted aggregation of bacterial cells and disorganization of bacterial cell wall and cytoplasmic membrane, which leads to the release of bacterial contents into the environment. These structural changes result in bacterial death.

