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Updated: Aug 14, 2026

Quantification of the Immunosuppressant Tacrolimus on Dried Blood Spots Using LC-MS/MS
Published on: November 8, 2015
Plasma cell balanitis treated with tacrolimus 0.1%
G A Moreno-Arias1, A Camps-Fresneda, C Llaberia
1Centro Médico Teknon, Despacho 27, Vilana 12, 08190 Barcelona, Spain. 935893067@telefonica.net
Background:
Plasma cell balanitis or balanitis of Zoon (BZ) is a frequent diagnosis in mature men and lesions are generally localized on the glans but may involve the prepuce; its aetiology remains unknown.
Objectives:
To present our experience with tacrolimus 0.1% ointment in the treatment of two patients with BZ refractive to other topical treatments.
Patients And Methods:
Two uncircumcised mature caucasian males were seen, both presenting with BZ; topical tacrolimus 0.1% ointment twice daily was prescribed in each case.
Results:
Marked improvement of the lesions in both patients has been observed, with follow-up of 1 year and 10 months, respectively.
Conclusions:
Topical tacrolimus 0.1% ointment is an effective and safe treatment for BZ.