Related Experiment Video
Updated: Aug 7, 2026

Derivation of Cardiac Progenitor Cells from Embryonic Stem Cells
Published on: January 12, 2015
[Embryonic stem cells to study early myocardial development and potential regenerative medicine]
1CNRS FRE2593, Centre de Recherches de Biochimie macromoléculaire, 1919, route de Mende, 34293 Montpellier Cedex, France. michel.puceat@crbm.cnrs.fr
Abstract:
Embryonic stem cells are capable to recapitulate the first stages of myocardial development. Using mouse embryonic stem cells, transcriptional networks specifying the cardiac fate can be delineated. Furthermore, using members of the TGFbeta superfamily to commit mouse ES cells toward a cardiac lineage, recent studies showed that ESC-derived cardiomyocytes were capable to repair post-infarcted myocardium of small and large animals. The next challenges are to validate such results using human ESCs in order to better comprehend cardiac congenital diseases and to foresee a cell therapy of heart failure. double dagger.
Related Concept Videos
Embryonic Stem Cells
Induced Pluripotent Stem Cells
Stem Cell Culture
Stem Cell Therapy for Tissue Regeneration
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...
Embryonic Stem Cells
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...
Induced Pluripotent Stem Cells
Somatic cells are...

