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Laser lipolysis using a novel 1,064 nm Nd:YAG Laser
1Laser and Skin surgery Center of New York, NY, USA. kim@laserskinsurgery.com
Summary
This study shows neodymium:yttrium-aluminum-garnet (Nd:YAG) laser lipolysis is safe and effective for reducing small fat areas. Patients experienced significant fat reduction and dermal tightening with minimal side effects.
Area of Science:
- Aesthetic Medicine
- Dermatology
- Medical Technology
Background:
- Investigated the safety and efficacy of 1,064 nm neodymium:yttrium-aluminum-garnet (Nd:YAG) laser with a 300-micron fiber.
- Focused on the reduction of small, localized unwanted fat areas.
Purpose of the Study:
- To evaluate the effectiveness of Nd:YAG laser lipolysis for fat reduction.
- To assess the safety profile and patient outcomes of the procedure.
- To explore potential dose-response relationships in fat volume reduction.
Main Methods:
- A study involving 30 subjects with focal fat areas under 100 cc.
- Treatment groups included laser lipolysis alone, laser lipolysis plus Tri-active system, and a control group.
- Magnetic resonance imaging (MRI) and self-assessment evaluations were used for data collection at baseline and 3-month follow-up.
Main Results:
- 29 subjects completed the study, reporting a 37% improvement in self-assessment.
- MRI revealed an average 17% reduction in fat volume.
- Submental areas showed better results, indicating a dose-response relationship. Mild bruising and swelling were the primary side effects.
Conclusions:
- Nd:YAG laser lipolysis with a 300-micron fiber is a safe and effective procedure for fat reduction.
- The treatment offers good, reproducible results with excellent patient tolerance and quick recovery.
- Dermal tightening is an additional benefit of this laser lipolysis technique.

