Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Coronary calcium scanning.

Ambarish Gopal1, Matthew J Budoff

  • 1Division of Cardiology, Los Angeles Biomedical Research Institute at Harbor-UCLA Research and Education Institute, Torrance, CA 90502, USA.

The American Heart Hospital Journal
|February 14, 2006
PubMed
Summary

Coronary artery calcium scoring is a cost-effective screening tool for intermediate-risk patients, significantly improving cardiovascular event prediction and prevention strategies.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Transcatheter Closure of Aortic Root Rupture and Pseudoaneurysm After Surgical Implantation of Transcatheter Valve in Native Mitral Annular Calcification With Concomitant Surgically Implanted Transcatheter Aortic Valve.

Structural heart : the journal of the Heart Team·2023
Same author

Simultaneous Kissing Balloon Inflation of the Transcatheter Aortic Valve Replacement Valve and an Ostial Coronary Stent-A Novel Coronary Protection Technique.

Structural heart : the journal of the Heart Team·2023
Same author

A Novel Computed Tomographic-Based Mitral Annular Calcium Score for Patients Who Underwent Transcatheter Aortic Valve Implantation.

The American journal of cardiology·2022
Same author

Usefulness of Thoracic Aortic Calcium to Predict 1-Year Mortality After Transcatheter Aortic Valve Implantation.

The American journal of cardiology·2020
Same author

Validation of a low-dose contrast 64-slice cardiac computed tomography angiography protocol for aortic valve annulus sizing.

Proceedings (Baylor University. Medical Center)·2019
Same author

Impact of Mitral Stenosis on Survival in Patients Undergoing Isolated Transcatheter Aortic Valve Implantation.

The American journal of cardiology·2019

Area of Science:

  • Cardiology
  • Preventive Medicine
  • Medical Imaging

Background:

  • Most cardiovascular events occur in intermediate-risk individuals (10%-20% 10-year risk).
  • Aggressive preventive therapy is crucial for high-risk patients (>20% 10-year risk).
  • Screening intermediate-risk patients is most cost-effective.

Purpose of the Study:

  • To evaluate the role of coronary artery calcium (CAC) scoring in cardiovascular risk assessment.
  • To determine if CAC scoring improves prediction of cardiovascular events beyond conventional risk factors.
  • To assess the cost-effectiveness of CAC screening in intermediate-risk populations.

Main Methods:

  • Utilizing electron beam tomography (EBT) and multidetector computed tomography (MDCT) to quantify coronary calcium.
  • Comparing the predictive performance of CAC scores against conventional risk factors, hs-CRP, and CTM.
  • Analyzing data on the association between elevated CAC scores and future cardiovascular events.

Main Results:

  • Coronary artery calcium is highly specific for atherosclerosis.
  • Elevated CAC scores independently and incrementally predict cardiovascular events.
  • Patients with increased CAC scores are ~10 times more likely to experience a cardiac event in 3-5 years.
  • CAC scoring outperformed conventional risk factors, hs-CRP, and CTM in predicting events.

Conclusions:

  • Coronary calcium detection significantly enhances global cardiovascular risk prediction.
  • CAC scoring provides noninvasive tracking of atherosclerotic burden.
  • CAC scoring improves the prediction of future cardiovascular events, especially in intermediate-risk individuals.

Related Experiment Videos