Related Experiment Videos
Clinical features of myomas.
Orhan Bukulmez1, Kevin J Doody
1Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, The University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75390-9032, USA. Obukul@parknet.pmh.org
Obstetrics and Gynecology Clinics of North America
|March 1, 2006
Summary
Uterine myomas, common pelvic tumors, often cause abnormal bleeding and discomfort. While usually benign, they can impact reproductive health and rarely transform into leiomyosarcomas.
Area of Science:
- Gynecology
- Oncology
Background:
- Uterine myomas are the most common solid pelvic tumors in women.
- They are a leading cause for hysterectomy and often asymptomatic.
- Common symptoms include abnormal uterine bleeding and pelvic discomfort.
Purpose of the Study:
- To review the clinical presentation and natural history of uterine myomas.
- To highlight their impact on reproductive health and potential for malignant transformation.
Main Methods:
- Review of existing literature on uterine myomas.
- Analysis of clinical data regarding symptoms, reproductive outcomes, and rare malignant changes.
Main Results:
- Most uterine myomas are asymptomatic; common symptoms are abnormal bleeding and mass effect.
- Myomas distorting the uterine cavity are linked to infertility and miscarriage.
- Malignant transformation to leiomyosarcoma is very rare, suspected in postmenopausal women with rapidly growing masses.
Conclusions:
- Uterine myomas significantly affect women's health, causing symptoms and reproductive issues.
- Further research is needed on the natural clinical history of these common tumors.