Comparison of simultaneous and sequential two-view registration for 3D/2D registration of vascular images

Accurate 3D/2D vessel registration is complicated by issues of image quality, occlusion, and other problems. This study performs a quantitative comparison of 3D/2D vessel registration in which vessels segmented from preoperative CT or MR are registered with biplane x-ray angiograms by either a) simultaneous two-view registration with advance calculation of the relative pose of the two views, or b) sequential registration with each view. We conclude on the basis of phantom studies that, even in the absence of image errors, simultaneous two-view registration is more accurate than sequential registration. In more complex settings, including clinical conditions, the relative accuracy of simultaneous two-view registration is even greater.