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Updated: Aug 8, 2026
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Oxygen-Induced Retinopathy Model for Ischemic Retinal Diseases in Rodents
Published on: September 16, 2020
Effect of ascovertin on morphological changes in rat retina exposed to high-intensity light
S V Logvinov1, M B Plotnikov, E Yu Varakuta
1Department of Histology, Embryology, and Cytology, Siberian State Medical University, Toms.
Bulletin of Experimental Biology and Medicine
|June 9, 2006
Abstract:
Experiments on rats showed that high-intensity light exposure (6000 lux, 6 h) caused focal injuries in the retina. The most sensitive structures were neurosensory cells, pigmented epithelium, radial gliocytes, and choroid capillaries. Injection of ascovertin led to disappearance of foci of injuries, limited blood supply disorders in the retina, and destruction of neurosensory and glial cells.
