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Related Experiment Videos

Allergen sequence databases.

Steven M Gendel1, John A Jenkins

  • 1Food and Drug Administration, National Center for Food Safety and Technology, Summit-Argo, Illinois 60501, USA. sgendel@cfsan.fda.gov

Molecular Nutrition & Food Research
|June 10, 2006
PubMed
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Specialized databases aid human allergen research by cataloging protein data, clinical information, and nomenclature. This review highlights key resources and discusses database quality factors for effective scientific study.

Area of Science:

  • Immunology
  • Bioinformatics
  • Computational Biology

Background:

  • Human allergen research relies on diverse data types, including molecular, clinical, and epidemiological information.
  • Specialized databases are crucial for organizing and accessing this complex information.
  • Existing resources vary in focus, from protein sequences to clinical data and nomenclature.

Purpose of the Study:

  • To review and describe existing specialized databases for human allergen research.
  • To provide examples of different types of allergen-related databases.
  • To discuss the construction, maintenance, and quality of these databases.

Main Methods:

  • Literature review of specialized databases.
  • Categorization of databases based on their data focus (molecular, informational, nomenclature).

Related Experiment Videos

  • Brief description and examples of identified databases.

    • Main Results:

    • Identification of multiple specialized databases for human allergens.
    • Categorization into molecular, clinical/biochemical/epidemiological, nomenclature, and peripheral knowledge bases.
    • Discussion of database construction, maintenance, and their impact on data quality.

    Conclusions:

    • A variety of specialized databases exist to support human allergen research.
    • Database quality and maintenance are critical for their utility in scientific studies.
    • These resources are essential for advancing our understanding of allergens.