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Escitalopram-induced uveal effusions and bilateral angle closure glaucoma
Joseph R Zelefsky1, Howard F Fine, Valeria J Rubinstein
1Manhattan Eye Ear and Throat Hospital, New York, NY 10016, USA. jzelefsk@yahoo.com
American Journal of Ophthalmology
|June 13, 2006
Summary
Escitalopram use can cause acute bilateral angle closure glaucoma due to ciliochoroidal effusions. Discontinuation of the drug and corticosteroid therapy resolved the condition.
Area of Science:
- Ophthalmology
- Pharmacology
Background:
- Selective serotonin reuptake inhibitors (SSRIs) are commonly prescribed for depression.
- Angle closure glaucoma is an ophthalmic emergency characterized by increased intraocular pressure.
Observation:
- A 41-year-old woman developed acute bilateral angle closure glaucoma after initiating escitalopram.
- Ophthalmic examination revealed ciliochoroidal effusions and angle closure.
Findings:
- High-frequency ultrasonography confirmed bilateral choroidal effusions with ciliary body detachment.
- Medical management including cycloplegics, corticosteroids, and escitalopram discontinuation led to symptom resolution.
Implications:
- This case highlights a potential adverse effect of escitalopram, leading to angle closure glaucoma.
- Early recognition and management, including drug cessation, are crucial for favorable outcomes in similar cases.
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