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Updated: Aug 7, 2026

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Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
[Anesthesia selection in hypophysectomy by endoscopic transnasal sphenoidal approach]
Qinxiu Zhang1, Jian Zou, Shixi Liu
1Department of Otolaryngology, West China Hospital of Sichuan University, Chengdu, 610041, China).
Summary
Local anesthesia with sedation is a safe and effective choice for endoscopic pituitary tumor removal. This approach ensures patient comfort and successful surgical outcomes for pituitary neoplasms.
Area of Science:
- Neurosurgery
- Anesthesiology
Background:
- Endoscopic transnasal sphenoidal approach is a minimally invasive technique for pituitary tumor resection.
- Anesthesia selection is crucial for patient safety and surgical success in these procedures.
Purpose of the Study:
- To evaluate the efficacy and safety of local anesthesia with sedation versus general anesthesia for pituitary tumor resection using the endoscopic transnasal sphenoidal approach.
Main Methods:
- A retrospective study of 56 patients undergoing endoscopic pituitary tumor resection.
- Patients were divided into two groups: general anesthesia (8 cases) and local anesthesia with sedation (48 cases).
Main Results:
- All patients tolerated the procedures well.
- The local anesthesia with sedation group experienced successful surgeries without intraoperative complications like struggling or restlessness.
- No patient complaints were reported in the local anesthesia group.
Conclusions:
- Local anesthesia with sedation is a simple, safe, and effective anesthetic option for pituitary tumor resection via the endoscopic transnasal sphenoidal approach.
- This technique offers a favorable patient experience and successful surgical outcomes.
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