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Updated: Aug 6, 2026

Percutaneous Contrast Echocardiography-guided Intramyocardial Injection and Cell Delivery in a Large Preclinical Model
Published on: January 21, 2018
Perflutren microspheres for contrast echocardiography in a bloody pericardiocentesis
José E Escabí-Mendoza1, Jorge D Martínez-Díaz, Eric D Avilés-Rivera
1The Cardiology Section, Department of Medicine, Veterans Administration Medical Center of San Juan, Puerto Rico. Jose.Escaabi@med.va.gov
Abstract:
We report the cases of 2 patients who presented with clinical and echocardiographic evidence of cardiac tamponade. Therapeutic echocardiographic-guided pericardiocentesis yielded bloody fluid. In both patients, Definity perflutren lipid microspheres were used for echocardiographic contrast, which helped to assess the needle's location. To the best of our knowledge, this is the 1st reported use of perflutren microspheres for this purpose.
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