Related Experiment Video
Updated: Jul 20, 2026

Therapeutic Massage for Psychological Well-being in Geriatric Oncology
Published on: May 22, 2026
Interpersonal psychotherapy for elderly patients in primary care
Anneke van Schaik1, Harm van Marwijk, Herman Adèr
1Department of Psychiatry, Department of General Practice, Institute for Research in Extramural Medicine (EMGO), VU University Medical Center, Amsterdam, The Netherlands. a.van.schaik@ggzba.nl
Interpersonal psychotherapy (IPT) significantly improved depression diagnosis rates in elderly patients compared to usual care. IPT was more effective for moderate to severe depression, enhancing social and mental functioning.
Area of Science:
- Geriatric Psychiatry
- Clinical Psychology
- Primary Care Medicine
Background:
- Interpersonal psychotherapy (IPT) is a recommended depression treatment, but its real-world effectiveness in elderly populations is understudied.
- General practitioners' usual care (CAU) is the standard for elderly depression in primary care settings.
Purpose of the Study:
- To compare the effectiveness of IPT delivered by mental health workers versus CAU in elderly patients with major depressive disorder.
- To evaluate IPT's impact on depression diagnosis and remission rates in a real-life practice setting.
Main Methods:
- A pragmatic randomized controlled trial involving 143 elderly patients with major depressive disorder.
- Patients were allocated to either 10 sessions of IPT or CAU.
- Primary outcomes assessed using the Primary care Evaluation of Mental Disorders (PRIME-MD) and Montgomery Asberg Depression Rating Scale (MADRS).
Main Results:
- IPT significantly reduced the percentage of patients diagnosed with depression (PRIME-MD) compared to CAU.
- IPT did not significantly increase remission rates (MADRS <10).
- Among treatment completers, IPT improved social and overall mental functioning; effectiveness was greater in moderately to severely depressed patients.
Conclusions:
- IPT is more effective than CAU for elderly patients with moderate to severe major depressive disorder in general practice.
- Further research is needed to identify factors influencing treatment outcomes in this population.
Related Concept Videos
Interpersonal Psychotherapy
Drug Dosing: Geriatric Patients
Psychodynamic Therapy
Pharmacodynamics in Geriatric Patients: Effects of Age
Peripheral Artery Disease III: Interprofessional Care
Interdisciplinary Care: The Health Care Team-I
Physicians
The physician's primary responsibility is to diagnose illness and direct the medical or surgical treatment of the condition. The authority to admit patients to a healthcare agency or institution and practice care within that setting is granted to physicians by the healthcare agency or institution itself.