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[Beta blocker induced depression. A case report].

F Acosta Artiles1, M Suárez Cabrera, M Acosta Artiles

  • 1Servicio de Psiquiatría. Hospital Universitario Insular de Gran Canaria. Las Palmas de Gran Canaria. Spain. fjacostaartiles@hotmail.com

Actas Espanolas De Psiquiatria
|September 23, 2006
PubMed
Summary
This summary is machine-generated.

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This case report suggests a link between beta blockers, specifically atenolol, and depression. The patient experienced depressive symptoms after starting atenolol, which resolved upon discontinuation.

Area of Science:

  • Pharmacology
  • Psychiatry
  • Cardiology

Background:

  • The association between beta blockers and depression remains controversial.
  • Evidence is largely based on case reports, with epidemiological studies and RCTs often showing no link.
  • Potential reasons for disparity include methodological challenges and weak association strength.

Observation:

  • A 67-year-old woman with no prior psychiatric history developed depression after starting atenolol.
  • Depressive symptoms rapidly improved after discontinuing atenolol.
  • A short course of antidepressant medication was also prescribed.

Findings:

  • This case suggests a potential association between atenolol use and the onset of a depressive episode.
  • The temporal relationship and symptom resolution support a drug-induced effect.

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Implications:

  • Highlights the importance of considering medication side effects in new-onset depression.
  • Suggests further investigation into the specific mechanisms linking beta blockers like atenolol to mood changes.
  • Informs clinical practice regarding patient monitoring during beta blocker therapy.