Related Experiment Video
Updated: Jul 19, 2026
09:03
Trabecular Meshwork Response to Pressure Elevation in the Living Human Eye
Published on: June 20, 2015
Tractional internal limiting membrane detachment in highly myopic eyes
Kaori Sayanagi1, Yasushi Ikuno, Yasuo Tano
1Department of Ophthalmology, Osaka University Medical School, Osaka, Suita, Japan.
American Journal of Ophthalmology
|October 24, 2006
Summary
Tractional internal limiting membrane (ILM) detachment is a significant finding in highly myopic eyes, often leading to myopic foveoschisis (MF). This condition is linked to the ILM's rigidity, causing tangential traction specific to high myopia.
Area of Science:
- Ophthalmology
- Retinal Imaging
- Myopia Research
Background:
- High myopia presents unique challenges in retinal health.
- Posterior staphyloma is a common complication in high myopia.
- Internal limiting membrane (ILM) abnormalities can impact retinal structure.
Purpose of the Study:
- To describe the clinical characteristics of tractional internal limiting membrane (ILM) detachment.
- To investigate this finding in eyes with high myopia and posterior staphyloma.
Main Methods:
- Retrospective review of optical coherence tomography (OCT) images.
- Analysis of 249 eyes from a high myopia clinic.
- Identification and characterization of six eyes (2.4%) with ILM detachment.
Main Results:
- Four out of six eyes (67%) exhibited myopic foveoschisis (MF).
- Patients had a mean age of 57.3 years, with a mean axial length of 29.3 mm and refractive error of -15.0 D.
- Best-corrected visual acuity varied significantly, ranging from 20/400 to 20/13.
Conclusions:
- The rigidity of the ILM appears to be a primary driver of tangential traction.
- This traction is a significant cause of myopic foveoschisis (MF), a condition specific to high myopia.
Related Concept Videos
01:25Glaucoma: Overview
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
01:17Accessory Structures of the Eye
Optical perception, or vision, is an extraordinary sense dependent on converting light signals received via the ocular organs. These organs, known as eyes, are securely positioned within the bony cavities of the skull, called orbits. The orbits serve a dual purpose: a protective shield for the ocular globes and a stable attachment point for the soft ocular tissues. The eye's external protective mechanisms include the eyelids, which are edged with lashes that act as a barrier against foreign...
01:16Focusing of Light in the Eye
Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...
01:20Muscles of the Eye
The muscles of the eye are sophisticated structures that control eye movement and focus, allowing for the precise and rapid adjustments necessary for vision. The human eye is controlled by ten muscles — six extraocular muscles, three intraocular muscles, and one primary eyelid retractor muscle.
Extraocular Muscles
The six extraocular muscles surround the eyeball and control its movements. They are responsible for a wide range of eye motions, including looking up, down, left, right, and rotating...
Extraocular Muscles
The six extraocular muscles surround the eyeball and control its movements. They are responsible for a wide range of eye motions, including looking up, down, left, right, and rotating...