Related Experiment Video
Updated: Jul 18, 2026
11:39
Subcellular Fractionation of Primary Chronic Lymphocytic Leukemia Cells to Monitor Nuclear/Cytoplasmic Protein Trafficking
Published on: October 23, 2019
[Primary effusion lymphoma]
P Khosravi Shahi1, P Sabín Domínguez, G Pérez Manga
1Servicio de Oncología Médica, Hospital General Universitario Gregorio Marañón, Dr. Esquerdo 46, 28007 Madrid.
Anales De Medicina Interna (Madrid, Spain : 1984)
|November 14, 2006
Summary
Primary effusion lymphoma, a rare cancer linked to human herpesvirus 8 (HHV-8) and HIV/AIDS, has a poor prognosis. This case highlights the aggressive nature of this lymphoma, with rapid progression and fatality within months.
Area of Science:
- Oncology
- Virology
- Hematology
Background:
- Primary effusion lymphoma (PEL) is a rare, aggressive non-Hodgkin lymphoma.
- PEL is strongly associated with human herpesvirus 8 (HHV-8) infection.
- PEL predominantly affects individuals with advanced HIV infection (AIDS).
Observation:
- A case report of a 65-year-old male patient is presented.
- The patient had a history of chronic hepatopathy, hemolytic anemia, and ascites.
- Peritoneal biopsy confirmed the diagnosis of primary effusion lymphoma.
Findings:
- The patient presented with symptoms including ascites and anemia.
- Diagnosis was confirmed via peritoneal biopsy.
- The patient had a median survival time of less than 6 months, dying two months post-diagnosis.
Implications:
- This case underscores the poor prognosis associated with PEL.
- Early diagnosis and management strategies for PEL are critical.
- Further research into HHV-8 associated lymphomas is warranted.
Related Concept Videos
01:16Primary Lymphoid Organs
Primary lymphoid organs are pivotal in the formation, development, and maturation of lymphocytes, the white blood cells that serve as the backbone of our immune system. This crucial function underscores their fundamental role in maintaining our overall health and immunity. The two primary lymphoid organs of prime importance are the red bone marrow and the thymus.
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
01:25Pleural Effusion I: Introduction
Pleural effusion is an abnormal fluid accumulation in the pleural cavity, a narrow space between the lungs and the chest wall. It is not a disease per se but rather a symptom or indication of an underlying disease. In normal circumstances, this space contains a small amount of fluid (5 to 15 mL), a lubricant facilitating the non-frictional movement of the pleural surfaces.
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's criteria,...
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's criteria,...
01:15Secondary Lymphoid Organs
Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
01:28Pleural Effusion II: Symptoms and Management
Pleural Effusion Overview
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations: