Related Experiment Video
Updated: Jul 18, 2026

11:49
Synthesis of Soft Polysiloxane-urea Elastomers for Intraocular Lens Application
Published on: March 8, 2019
Synchrony dual-optic accommodating intraocular lens. Part 2: pilot clinical evaluation
Ivan L Ossma1, Andrea Galvis, Luis G Vargas
1Department of Ophthalmology, Fundacion Oftalmologica de Santander, Bucaramanga, Colombia.
Journal of Cataract and Refractive Surgery
|December 27, 2006
Summary
The Synchrony dual-optic intraocular lens (IOL) offers improved accommodative function for pseudophakic patients. This accommodating IOL demonstrated a significantly greater accommodative range compared to traditional monofocal IOLs.
Area of Science:
- Ophthalmology
- Biomedical Engineering
- Retinal Science
Background:
- Cataract surgery often results in a loss of natural accommodation.
- Intraocular lenses (IOLs) aim to restore visual function after cataract removal.
- Accommodating IOLs are designed to mimic the eye's natural focusing ability.
Purpose of the Study:
- To assess the clinical performance of the Synchrony dual-optic accommodating intraocular lens (IOL).
- To compare the accommodative range of the accommodating IOL with a control group.
Main Methods:
- A prospective case series with a retrospective control group was conducted.
- 21 patients received the Synchrony dual-optic accommodating IOL, compared to 10 patients with a monofocal IOL.
- Visual acuity and accommodative range via defocus curves were measured at multiple follow-up intervals.
Main Results:
- All eyes achieved a best-corrected distance visual acuity of 20/40 or better.
- Uncorrected near visual acuity was 20/40 or better in all patients.
- The accommodating IOL group showed a significantly greater mean accommodative range (3.22 D) versus the control group (1.65 D).
Conclusions:
- The Synchrony dual-optic IOL shows potential for restoring accommodative function in pseudophakic eyes.
- This accommodating IOL represents a promising option for patients seeking improved near vision after cataract surgery.
Related Concept Videos
Angle Closure Glaucoma: Treatment
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Open Angle Glaucoma: Treatment
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
Glaucoma: Overview
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Ophthalmic Drug Delivery Systems
Ophthalmic drug delivery faces major limitations due to poor absorption across the corneal membrane. This process is primarily driven by diffusion and is influenced by two main factors: the physicochemical properties of the drug and tear drainage. Most ophthalmic drugs, such as pilocarpine, epinephrine, atropine, and local anesthetics, are weak bases. They are typically formulated at an acidic pH to enhance chemical stability. However, this leads to high ionization, reducing their ability to...

