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Updated: Jul 18, 2026

In Vivo Modeling of the Morbid Human Genome using Danio rerio
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Toward whole cell modeling and simulation: comprehensive functional genomics through the constraint-based approach.

Andrew R Joyce1, Bernhard O Palsson

  • 1Bioinformatics Program, University of California, San Diego, La Jolla, California, USA. ajoyce@ucsd.edu

Progress in Drug Research. Fortschritte Der Arzneimittelforschung. Progres Des Recherches Pharmaceutiques
|January 2, 2007
PubMed
Summary

Constraint-based modeling uses omics data to build genome-scale metabolic models. This approach distinguishes achievable states, aiding hypothesis testing and predicting phenotypes for drug development.

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