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Updated: Jul 17, 2026

Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
Published on: November 4, 2025
[Disturbances of growth and development of the maxillofacial skeleton]
A G Becking1, Th J M Hoppenreijs, D B Tuinzing
1Afdelingen Mondziekten en Kaakchirurgie/Orale Pathologie van het Vrije Universiteit Medisch Centrum, Amsterdam. ag.becking@vumc.nl
Abstract:
Due to many developments in oral and maxillofacial surgery, the contribution of oral and maxillofacial surgeons in the diagnostics and treatment of growth and development disorders of the craniomandibulo-maxillofacial skeleton has become more and more important. Many disorders are treated by multidisciplinary teams including orthodontists and prosthodontists. Arbitrarily, 3 categories of growth and developmental disorders can be distinguished: dento-alveolar, dento-maxillofacial, and dento-maxillo-craniofacial disorders. In addition to classic bony reconstruction methods, new methodologies have been developed, such as distraction osteogenesis and simultaneous skin and soft tissue corrections. For many decades, the treatment of growth and development disorders has been a frequent subject of doctoral dissertations in The Netherlands. Attention is currently being paid to developing methods for three-dimensional planning and correction of these disorders, and methods which are minimally invasive.
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