Related Experiment Video
Updated: Jul 17, 2026

Shifting Zebrafish Lethal Skeletal Mutant Penetrance by Progeny Testing
Published on: September 1, 2017
Reciprocal gene loss between Tetraodon and zebrafish after whole genome duplication in their ancestor
1Smurfit Institute of Genetics, Trinity College Dublin, Dublin 2, Ireland.
Abstract:
The whole genome duplication that occurred in ray-finned fish coincided with the radiation of teleost species; consequently, these two phenomena have often been linked. Using the Tetraodon and zebrafish complete genome sequences, we tested a molecular hypothesis that can relate whole genome duplication to speciation in teleosts. We estimate that thousands of genes that remained duplicated when Tetraodon and zebrafish diverged underwent reciprocal loss subsequently in these two species, probably contributing to reproductive isolation between them.
Related Concept Videos
Gene Duplication and Divergence
The duplicated copies of the gene are called Paralogs. Paralogs with similar sequences and functions form a gene family. Across several species, a large number of gene families are characterized.
Gene Families
Occasionally these regions can be adapted to take on new roles within the organism, becoming novel genes...

