Synergistic effect of intravenous immunoglobulins and iodinated contrast media on renal function

Mojgan Safari1, Seyed Hesamedin Nabavizadeh, Sara Kashef

  • 1Department of Pediatric Immunology and Allergy, Shiraz University of Medical Sciences, Shiraz, Iran. mo_sfr@yahoo.com.

Acute renal failure is one of the side effects while using intravenous immunoglobulins. This complication is also observed with iodinated contrast media. Herein, we describe a patient with acute renal failure who received intravenous immunoglobulins and iodinated contrast media concomitantly. Both drugs are responsible for osmotic nephrosis. The same effect on renal cells may explain a synergistic effect on renal function.

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