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Synergistic effect of intravenous immunoglobulins and iodinated contrast media on renal function
Mojgan Safari1, Seyed Hesamedin Nabavizadeh, Sara Kashef
1Department of Pediatric Immunology and Allergy, Shiraz University of Medical Sciences, Shiraz, Iran. mo_sfr@yahoo.com.
Acute renal failure is one of the side effects while using intravenous immunoglobulins. This complication is also observed with iodinated contrast media. Herein, we describe a patient with acute renal failure who received intravenous immunoglobulins and iodinated contrast media concomitantly. Both drugs are responsible for osmotic nephrosis. The same effect on renal cells may explain a synergistic effect on renal function.
Acute renal failure is one of the side effects while using intravenous immunoglobulins. This complication is also observed with iodinated contrast media. Herein, we describe a patient with acute renal failure who received intravenous immunoglobulins and iodinated contrast media concomitantly. Both drugs are responsible for osmotic nephrosis. The same effect on renal cells may explain a synergistic effect on renal function.
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