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Intrauterine insemination outperforms intracervical insemination in a randomized, controlled study with frozen, donor
P E Patton1, K A Burry, A Thurmond
1Department of Obstetrics and Gynecology, Oregon Health Sciences University, Portland.
Objective:
To assess the efficacy of intrauterine insemination (IUI) in a donor insemination program.
Design:
Prospective randomized clinical trial.
Setting:
Donor insemination program.
Patients, Participants:
Women undergoing insemination were randomly assigned to receive either IUI or intracervical insemination for a maximum of six cycles.
Interventions:
None.
Main Outcome Measure(S):
Cycle fecundity rates between the two routes were compared.
Results:
The monthly fecundity rate for intracervical insemination was 5.1% compared with 23% by IUI. By life table analysis, pregnancy rates for IUI were significantly higher than intracervical insemination (P = 0.02).
Conclusions:
Intrauterine insemination with quarantined donor sperm is superior to intracervical insemination.