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Updated: Jul 15, 2026

An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota
Published on: July 31, 2019
Prebiotics, probiotics, and dietary fiber in gastrointestinal disease
Jacqueline Park1, Martin H Floch
1Digestive Disease Section, Yale University School of Medicine, 333 Cedar Street, 1080 LMP, PO Box 208019, New Haven, CT 06520, USA.
Abstract:
Microecology of the gastrointestinal tract is the physiologic basis for the effect of dietary fiber, prebiotics and probiotics on the host. The ecology consists of the gastrointestinal tract, primarily the intestines, the foods that are fed into the tract, and the flora living within. Within this ecology, normal flora and probiotics, ferment dietary fiber and prebiotics to produce short chain fatty acids and substances that are absorbed and effect the host at the intestinal level and systemically. In this review, we will discuss the effects of prebiotics, probiotics and dietary fiber in gastrointestinal disorders and diseases.
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