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Published on: March 9, 2017
Ductal carcinoma in situ--current management
Martin J O'Sullivan1, Monica Morrow
1Department of Surgical Oncology, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111-2497, USA.
The Surgical Clinics of North America
|May 15, 2007
Summary
This review covers modern management for ductal carcinoma in situ (DCIS), detailing surgical options like mastectomy and sentinel node biopsy. It also discusses radiation therapy and tamoxifen use for DCIS treatment.
Area of Science:
- Oncology
- Breast Surgery
- Radiation Oncology
Background:
- Ductal carcinoma in situ (DCIS) is a non-invasive form of breast cancer.
- Optimal management strategies for DCIS continue to evolve.
- Evidence-based guidelines are crucial for patient care.
Purpose of the Study:
- To summarize current evidence-based management of ductal carcinoma in situ (DCIS).
- To present data on surgical considerations, including mastectomy and sentinel node biopsy.
- To discuss the role of adjuvant therapies like radiation and tamoxifen.
Main Methods:
- Literature review of randomized trials and clinical data.
- Analysis of surgical techniques and indications.
- Evaluation of evidence for radiation therapy and hormonal therapy.
Main Results:
- Surgical management decisions, including mastectomy indications and sentinel node biopsy utility, are presented.
- The efficacy of radiation therapy post-breast-conserving surgery for DCIS is examined.
- The role of tamoxifen in DCIS treatment is discussed based on clinical trial data.
Conclusions:
- Management of DCIS requires consideration of individual patient factors.
- Evidence supports various treatment modalities, including surgery, radiation, and hormonal therapy.
- Personalized treatment strategies are essential for optimal outcomes in DCIS management.
