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[Prevalence of coeliac disease (CD) in children with type 1 diabetes (T1D)]

Dorte Hansen1, Bendt Brock-Jacobsen, Elisabeth Lund

  • 1Odense Universitetshospital, Paediatrisk Afdeling. dorte.hansen@dadlnet.dk

Ugeskrift for Laeger
|June 8, 2007
PubMed

Insights

Screening for coeliac disease (CD) in children with type 1 diabetes (T1D) identified a 12.3% prevalence. A gluten-free diet improved clinical outcomes in these pediatric patients.

Area of Science:

  • Pediatric Endocrinology
  • Gastroenterology
  • Immunology

Context:

  • Type 1 diabetes (T1D) is an autoimmune condition affecting children.
  • Coeliac disease (CD) is an autoimmune disorder triggered by gluten.
  • The co-occurrence of T1D and CD in pediatric populations warrants investigation.

Purpose:

  • To determine the prevalence of coeliac disease (CD) in children diagnosed with type 1 diabetes (T1D).
  • To evaluate the clinical effects of implementing a gluten-free diet in children with T1D and CD.

Summary:

  • A screening study in Southern Denmark identified 269 children under 16 with T1D.
  • Coeliac disease was diagnosed in 33 patients (12.3%), who were younger at diabetes onset and had lower height and weight SDS.
  • Following a 2-year gluten-free diet, significant improvements in clinical and biochemical parameters were observed.

Impact:

  • Highlights the high prevalence of CD in children with T1D, suggesting a need for routine screening.
  • Demonstrates the clinical benefits of a gluten-free diet for pediatric patients with co-occurring T1D and CD.
  • Informs clinical practice guidelines for managing children with type 1 diabetes.

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