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Updated: Oct 23, 2026

Detrusor Underactivity Model in Rats by Conus Medullaris Transection
Published on: August 28, 2020
[Sacral nerve modulation for urinary disorders]
Sheida Anvari Aria1, Margrethe Andersen1,2, Rie Seifert3
1Urologisk Afdeling, Odense Universitetshospital.
Abstract:
Overactive bladder and non-obstructive urinary retention are highly prevalent urological conditions with substantial impact on patients' quality of life. Following comprehensive clinical evaluation, sacral nerve modulation (SNM) may be considered in patients with insufficient response to first- and second-line therapies. SNM is a minimally invasive, reversible therapy which modulates signaling in the sacral nerve roots restoring bladder and pelvic floor function. The therapy has demonstrated durable efficacy and safety. Optimal outcomes with SNM depend on careful patient selection in a multidisciplinary setting, as argued in this review.
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