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Updated: Jul 14, 2026

Correction of Presbyopia by Monocular Bi-Aspheric Ablation Profile
Published on: September 20, 2024
Corneal wavefront-guided ablation with the Schwind ESIRIS laser for myopia
Chuanqing Zhou1, Min Jin, Xiaoyuan Wang
1Laboratory of Ophthalmology & Visual Optics, Institute for Laser Medicine and Bio-Photonics, Department of Biomedical Engineering, College of Life Science and Technology, Shanghai Jiaotong University, Shanghai, China.
Corneal wavefront-guided LASIK effectively treats myopia and astigmatism, achieving high visual acuity and refractive accuracy. Post-treatment, higher-order aberrations increased, but the procedure remains safe and effective.
Area of Science:
- Ophthalmology
- Refractive Surgery
- Wavefront Aberrometry
Background:
- Myopia and myopic astigmatism are common refractive errors.
- Laser-assisted in situ keratomileusis (LASIK) is a widely used refractive surgery.
- Corneal wavefront analysis offers potential for customized refractive correction.
Purpose of the Study:
- To assess the safety, efficacy, and predictability of corneal wavefront-guided LASIK.
- To evaluate visual outcomes, including uncorrected visual acuity and refractive error.
- To analyze changes in corneal higher-order wavefront aberrations and contrast sensitivity.
Main Methods:
- 56 myopic eyes with astigmatism underwent corneal wavefront analysis.
- Customized ablation profiles were generated using preoperative wavefront data and manifest refraction.
- Safety, efficacy, predictability, contrast sensitivity, and higher-order aberrations were evaluated at 1-year follow-up.
Main Results:
- Mean residual refractive error was -0.15 +/- 0.3 D; 95% of eyes achieved +/- 0.50 D correction.
- Uncorrected visual acuity improved by 1.00 D or better in 94% of eyes.
- Corneal higher-order aberrations increased significantly postoperatively; contrast sensitivity showed minor reductions with glare.
Conclusions:
- Corneal wavefront-guided LASIK is a safe and effective treatment for myopia and myopic astigmatism.
- The procedure leads to significant improvements in visual acuity and refractive accuracy.
- An increase in higher-order aberrations is a notable postoperative finding.
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