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Updated: Jul 13, 2026

The Pocket-Creation Procedure of Endoscopic Submucosal Dissection for Large Rectal Laterally Spreading Tumors
Published on: February 13, 2026
Novel techniques and instrumentation for EMR, ESD, and full-thickness endoscopic luminal resection
Kazuki Sumiyama1, Christopher J Gostout
1Mayo Clinic, Developmental Endoscopy Unit, Charlton 8-A, 200 First Street, SW, Rochester, MN 55905, USA.
Abstract:
Endoscopic intervention is evolving into an established therapeutic alternative for small superficial lesions, and an eventual application for en bloc resection of large lesions, deeper layers, and a reliable access to lesions outside of the gastrointestinal wall. Although further developmental and clinical evaluation is necessary, we believe endoscopic resection by the submucosal route and by full-thickness approaches will replace standard surgical procedures in the next several years.
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