Related Experiment Video
Updated: Jul 12, 2026

05:31
OP-IVM: Combining In vitro Maturation after Oocyte Retrieval with Gynecological Surgery
Published on: May 9, 2021
[Intrauterine insemination: against systematic ovarian stimulation]
1Unité de biologie de la reproduction-CECOS de l'Ouest, CHR Hôtel-Dieu, 1 bis, rue de la Cochardière, 35000 Rennes, France. dominique.lelannou@chu-rennes.fr
Gynecologie, Obstetrique & Fertilite
|August 28, 2007
Summary
Intrauterine insemination (IUI) is a primary infertility treatment. While often combined with ovulation stimulation, the benefit of stimulation requires careful consideration for each case, especially regarding multiple pregnancies.
Area of Science:
- Reproductive Medicine
- Infertility Treatments
Context:
- Intrauterine insemination (IUI) is a first-line treatment for various non-tubal infertility cases.
- IUI is frequently coupled with ovulation stimulation to synchronize insemination with ovulation and enhance follicular recruitment.
Purpose:
- To evaluate the role and necessity of ovulation stimulation when performing intrauterine insemination.
- To discuss the indications for ovulation stimulation in conjunction with IUI, considering its impact on pregnancy rates and multiple gestations.
Summary:
- Intrauterine insemination (IUI) is a key procedure for infertility.
- Ovulation stimulation, though often used with IUI, does not universally improve outcomes and its necessity must be individualized.
- The use of ovulation stimulation is a determining factor in the occurrence of multiple pregnancies.
Impact:
- Provides guidance on the judicious use of ovulation stimulation alongside IUI.
- Highlights the risks of multiple pregnancies associated with stimulated IUI cycles.
- Aids clinicians in optimizing IUI protocols for better patient outcomes and safety.
Related Concept Videos
In Vitro Fertilization
In vitro fertilization (IVF) is a form of assisted reproductive technology where an egg is fertilized with sperm in a controlled laboratory environment before transferring the resulting embryo into the uterus. This process is designed to help individuals and couples experiencing difficulties conceiving.
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
Intrauterine Drug Delivery Systems
Controlled-release systems for intravaginal and intrauterine drug delivery have been developed primarily for the administration of contraceptive steroid hormones. These delivery routes circumvent first-pass hepatic metabolism, thereby enhancing bioavailability and allowing for reduced systemic dosages compared to oral administration. Such approaches contribute to improved therapeutic efficacy and patient compliance, particularly in long-term contraceptive regimens.Intravaginal Drug Delivery...
Ovarian Cycle
The menstrual cycle includes a critical component known as the ovarian cycle, which undergoes two main phases each month—the follicular phase and the luteal phase. The follicular phase is variable and averaging around 14 days. Ovulation, triggered by a surge in luteinizing hormone (LH), marks the transition between the two phases. The second phase, the luteal phase, is relatively consistent, lasting approximately 14 days, and is marked by the activity of the corpus luteum. While a cycle length...
Meiosis II
Meiosis II is the second and final stage of meiosis. It relies on the haploid cells produced during meiosis I, each of which contain only 23 chromosomes—one from each homologous initial pair. Importantly, each chromosome in these cells is composed of two joined copies, and when these cells enter meiosis II, the goal is to separate such sister chromatids using the same microtubule-based network employed in other division processes. The result of meiosis II is two haploid cells, each containing...
