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Updated: Jul 11, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Extracranial stenosis: endovascular treatment
1David Geffen School of Medicine at UCLA, Division of Interventional Neuroradiology, 10833 Le Conte Avenue, BL-133 CHS, Los Angeles, CA 90095, USA. yloh@mednet.ucla.edu
Insights
Stroke, a leading cause of death, affects nearly 700,000 Americans annually. This article focuses on atherosclerotic carotid stenoses amenable to revascularization procedures.
Area of Science:
- Neurology
- Vascular Surgery
- Cardiology
Background:
- Stroke is a major cause of death and disability in the US, with significant economic impact.
- Atherosclerotic disease accounts for one-third of strokes, often involving extracranial locations.
- Carotid stenoses, typically unifocal and near the carotid bulb, are a primary concern.
Purpose of the Study:
- To review stenoses amenable to revascularization.
- To discuss current treatment modalities for carotid artery stenosis.
Main Methods:
- Review of current literature on carotid stenosis and revascularization.
- Analysis of epidemiological data on stroke incidence and costs.
- Comparison of carotid endarterectomy and carotid angioplasty/stenting procedures.
Main Results:
- Atherosclerotic disease is a significant cause of stroke, particularly extracranial carotid stenoses.
- Carotid endarterectomy is the more common surgical revascularization procedure.
- Carotid angioplasty and stenting are performed less frequently.
Conclusions:
- Understanding carotid stenoses amenable to revascularization is crucial for stroke prevention.
- The article provides an overview of current interventional approaches.
- Further research may optimize treatment strategies for carotid artery disease.
Abstract:
Stroke is the third-leading cause of death in the United States. It occurs in almost 700,000 people per year and cost an estimated US dollars 57.9 billion in 2006. Atherosclerotic disease is the cause of one third of these strokes, with more than one half of these stenoses being extracranial in location. Carotid stenoses are usually unifocal and 90% occur within 2 cm of the carotid bulb. Currently, carotid endarterectomy accounts for 117,000 surgical revascularizations per year, whereas carotid angioplasty and stenting are performed less than 10,000 times annually. Stenoses amenable to revascularization are the topic of this article.
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