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Updated: Jul 11, 2026
07:56
Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
Published on: January 29, 2018
One-year-old male with accelerated growth and development
Ajit Singh Kashyap1, Kuldip Parkash Anand, Surekha Kashyap
1Department of Endocrinology, Command Hospital (Central Command), Lucknow Cantt, India. kashyapajits@gmail.com
Postgraduate Medical Journal
|October 6, 2007
Summary
A rare case of precocious puberty in a 1-year-old boy was diagnosed using neuroimaging and successfully treated with gonadotropin-releasing hormone agonist analogues.
Area of Science:
- Pediatric Endocrinology
- Pediatric Neurology
- Neuroimaging
Background:
- Isosexual central (gonadotropin-dependent) precocious puberty is a condition characterized by early onset of pubertal development.
- Hypothalamic hamartomas are rare congenital brain tumors that can cause central precocious puberty.
Observation:
- A 1-year-old male child presented with symptoms of precocious puberty.
- Neuroimaging revealed a hypothalamic hamartoma as the likely cause.
Findings:
- The diagnosis of central precocious puberty was established based solely on characteristic neuroimaging findings.
- Medical treatment with gonadotropin-releasing hormone agonist analogues resulted in satisfactory suppression of pubertal progression.
Implications:
- This case highlights the importance of neuroimaging in diagnosing central precocious puberty.
- Gonadotropin-releasing hormone agonist analogues are an effective treatment for precocious puberty caused by hypothalamic hamartoma.
- Early diagnosis and treatment can prevent long-term adverse effects of precocious puberty.
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