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Updated: Jul 11, 2026

Preparation and Culture of Myogenic Precursor Cells/Primary Myoblasts from Skeletal Muscle of Adult and Aged Humans
10:10

Preparation and Culture of Myogenic Precursor Cells/Primary Myoblasts from Skeletal Muscle of Adult and Aged Humans

Published on: February 16, 2017

Intrinsic changes and extrinsic influences of myogenic stem cell function during aging

Andrew S Brack1, Thomas A Rando

  • 1Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305-5235, USA.

Stem Cell Reviews
|October 6, 2007
PubMed
Summary

Aging impairs skeletal muscle regeneration by affecting the function of myogenic stem cells (satellite cells) and their surrounding environment. Understanding these stem cell-environment interactions is key for developing therapies for age-related muscle decline.

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