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Polymer microfabrication technologies for microfluidic systems.

Holger Becker1, Claudia Gärtner

  • 1microfluidic ChipShop GmbH, Carl-Zeiss-Promenade 10, 07745, Jena, Germany. hb@microfluidic-chipshop.com

Analytical and Bioanalytical Chemistry
|November 9, 2007
PubMed
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Polymers are leading substrate materials for microfluidic devices due to their versatile properties. This review covers key fabrication technologies for polymer microfluidic systems, including replication and photodefining methods.

Area of Science:

  • Materials Science
  • Engineering
  • Microfluidics

Background:

  • Polymers are increasingly utilized as substrate materials for microfluidic devices.
  • They offer unique material and surface properties enabling advanced microscopic designs.
  • A diverse array of fabrication technologies are available for polymer-based microfluidics.

Purpose of the Study:

  • To review current microfabrication technologies for polymer microfluidic systems.
  • To discuss academic and industrial considerations for these fabrication methods.
  • To provide a comprehensive overview including back-end processing.

Main Methods:

  • Replication methods: hot embossing, injection molding, microthermoforming, casting.
  • Photodefining methods: lithography, laser ablation.

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  • Discussion of academic and industrial factors.
  • Main Results:

    • Polymers provide unparalleled design flexibility for microfluidic devices.
    • Various fabrication techniques offer distinct advantages for different applications.
    • Back-end processing is a crucial, often overlooked, aspect.

    Conclusions:

    • The selection of fabrication technology depends on specific academic and industrial requirements.
    • Continued advancements in polymer microfabrication are essential for the field.
    • A holistic approach considering all processing steps is vital for successful microfluidic device development.