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The Zebrafish Information Network: the zebrafish model organism database provides expanded support for genotypes and
Judy Sprague1, Leyla Bayraktaroglu, Yvonne Bradford
1The Zebrafish Information Network, 5291 University of Oregon, Eugene, OR 97403-5291, USA. judys@cs.uoregon.edu
Nucleic Acids Research
|November 10, 2007
Summary
The Zebrafish Information Network (ZFIN) is a comprehensive database for zebrafish genetic and developmental data. It enhances research by integrating diverse data types and providing advanced search and annotation tools.
Area of Science:
- * Developmental Biology
- * Genomics
- * Bioinformatics
Background:
- * The Zebrafish Information Network (ZFIN) serves as a central repository for curated zebrafish genetic, genomic, and developmental data.
- * Zebrafish are a key model organism for studying gene function, development, behavior, and disease.
Purpose of the Study:
- * To provide an integrated platform for accessing and analyzing zebrafish data.
- * To enhance the utility of ZFIN through recent updates and expanded functionalities.
Main Methods:
- * Data integration of mutant phenotypes, genes, expression patterns, sequences, genetic markers, and more.
- * Web-based query forms and bulk data file access.
- * Development and application of ontologies, including anatomical ontology (AO) and gene ontology (GO).
Main Results:
- * ZFIN offers extensive data integration, facilitating zebrafish research.
- * It is the definitive source for zebrafish gene nomenclature, AO, and GO annotations.
- * Recent enhancements include an improved interface, expanded genotype/phenotype support, and integrated BLAST search.
Conclusions:
- * ZFIN is an essential resource for the zebrafish research community.
- * Ongoing development ensures ZFIN remains a leading model organism database.
- * Enhanced features improve data accessibility and analytical capabilities for researchers.
