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Updated: Jul 10, 2026

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Brain-Computer Interface-controlled Upper Limb Robotic System for Enhancing Daily Activities in Stroke Patients
Published on: April 18, 2025
ZigBee-based wireless intra-oral control system for quadriplegic patients.
1Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA. qiyupeng@gmail.com
Summary
This study presents a tongue-controlled, wireless human-to-computer system using the ZigBee protocol. It enhances the quality of life for patients with stroke and spinal cord injury by enabling device control.
Area of Science:
- Biomedical Engineering
- Human-Computer Interaction
- Assistive Technology
Background:
- Patients with severe motor impairments, such as those from stroke or spinal cord injury, often face significant challenges in controlling external devices.
- Existing assistive technologies may be costly, power-intensive, or lack seamless integration for comprehensive environmental control.
Purpose of the Study:
- To develop and present a novel wireless human-to-computer interface system controlled by tongue movements.
- To leverage the ZigBee protocol for reliable, low-power, and cost-effective communication within the system.
- To enhance the quality of life for individuals with limited mobility by providing intuitive control over various devices.
Main Methods:
- The system comprises a wireless intra-oral module with five buttons, a wireless coordinator, and distributed wireless controllers.
- The ZigBee protocol was implemented to ensure robust and energy-efficient wireless data transmission.
- User interaction is facilitated by manipulating the intra-oral module buttons with the tongue.
Main Results:
- The developed system enables users to control computer cursors, menus, wheelchairs, lights, televisions, phones, and robotic devices.
- The ZigBee protocol demonstrated reliable and low-power communication, crucial for an intra-oral device.
- The system offers a cost-efficient solution for assistive control.
Conclusions:
- The presented tongue-controlled wireless system offers a viable and effective assistive technology for individuals with stroke and spinal cord injuries.
- This innovation has the potential to significantly improve patient autonomy and quality of life.
- The use of the ZigBee protocol makes the system accessible and practical for widespread adoption.

