Related Experiment Video
Updated: Jul 10, 2026
Translational Rabbit Model of Chronic Cardiac Pacing
Published on: January 6, 2023
Comparison of results with different left ventricular pacing leads
Eyal Nof1, Osnat Gurevitz, Shemy Carraso
1Heart Institute, Sheba Medical Center and Sackler Faculty of Medicine, Tel Aviv University, 52621 Tel Hashomer, Tel Aviv, Israel. ernof@netvision.net.il
Aims:
To compare different coronary sinus (CS) leads and delivery systems (DSs) for left ventricular pacing.
Methods And Results:
Delivery systems-related (including CS dissection and dislocations during sheath/stylet removal) and lead-related (including failure to accomplish implantations and long-term malfunctions resulting in abandonment or repositioning/replacing of the lead) complications between systems and leads were compared. We used Medtronic (MDT) attain DS (n = 123) with over-the-wire (OTW) (4193, 4194) and stylet-driven (2187) leads, and Guidant (GDT) DS (n = 126) with Easytrak OTW leads (4513, 4518, and 4525). Coronory sinus dissection occurred in 6/123 (5%) cases using the MDT DS vs. 7/126 (6%) with GDT DS (P= NS). Dislocations during sheath/stylet removal occurred in 8/123 cases (6%) with MDT DS, and in 8/126 (6%) with GDT DS (P= NS). Failure to achieve successful implantation occurred in 6/32 (19%) of the 2187 leads, in 11/87(13%) of the 4193/4194 leads, in 7/94(7%) of the 4513/4518 leads, and in 4/29 (14%) of the 4525 leads (P= NS). Long-term lead-related complications occurred in 5/32 (15%) of the 2187 leads, 19/80 (23%) of the 4193/4194 leads, 19/93 (20%) of the 4513/4518 leads, and 2/28 (7%) of the 4525 leads (P= NS).
Conclusion:
No significant differences in complication rates between systems and leads were observed.
