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Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids
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Promotion of PNA double-duplex invasion by glutaric dialdehyde

Yoshitaka Miyajima1, Yoji Yamamoto, Makoto Komiyama

  • 1Research Center for Advanced Science and Technology, The University of Tokyo, 4-6-1 komaba, Meguro-ku, Tokyo, 153-8904, Japan.

Nucleic Acids Symposium Series (2004)
|November 22, 2007
PubMed

Abstract:

Invasion of two pseudo-complementary PNA additives (pcPNAs) to target site in double-stranded DNA (double-duplex invasion) was greatly promoted by the addition of glutaric dialdehyde.

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