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Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids
Published on: September 21, 2017
Structure and excimer fluorescence of helical-pyrene-arrays assembled on duplex RNA
Mitsunobu Nakamura1, Kazushige Yamana, Yukinori Simomura
1Department of Materials Science and Chemistry, Graduate School of Engineering, University of Hyogo, 2167 Shosha, Himeji, Hyogo 671-2201, Japan. mitunobu@eng.u-hyogo.ac.jp
Abstract:
The helical pyrene arrangement on duplex RNA has been evident from the computer simulations that gave the circular dichroism (CD) bands being well consistent with the experimentally observed CD. The pyrene-arrays exhibit the strong excimer fluorescence whose intensity is dependent on the nucleotide sequences and contexts of duplex RNA.
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